My Wife and I have found that this roll-on is a huge help with our migraines; rolling it on our temples, base of the skull, or along the line of pain helps. I also used it to nurse a repetitive motion injury back to health. I keep 1 in my purse and 1 on the nightstand, so I always have it handy. The 0% THC factor is very important to me. I can have relief without risk.